Hypersensitivity to light, noise, odors and climate change are common; These sensitivities are generally explained by hypervigilance, which is observed in the nervous system of patients with fibromyalgia.
Neurogenic inflammation (uncontrolled due to a condition of the brain, spinal cord, or nerves), a discrete localized inflammatory response that does not stimulate an immune response or a test is detected , appears to play a role in itching and rashes. skin observed in patients with fibromyalgia.
Allergic-type reactions to a number of substances (e.g. drugs, chemicals, food additives, contaminants, etc.) are common and patients may present with a non-allergic form of rhinitis characterized by constipation or runny nose and pain in the nasal sinuses. but without the immune reactions that occur under allergic conditions.
Possible causes: Medical studies on fibromyalgia have aimed to analyze whether there are muscle damage, changes in the immune system, psychological abnormalities, hormonal problems, or, as noted above, changes in the protective mechanisms of pain.
Low levels of some important pain-regulating substances (especially serotonin ) have been found in the nervous system of people with fibromyalgia .