Fibromyalgia Pain May Be Linked To Spinal Cord Dysfunction, Researchers Find

According to a study titled “Elongated Silent Skin Period in Fibromyalgia Suggesting Central Sensitization as Pathogenesis” and published in the journal PLOS One, dysfunction in spinal cord processing may be responsible for pain in patients with fibromyalgia (FM) .

Among other side effects, fibromyalgia is represented by chronic widespread pain, but the root cause that is responsible for chronic pain in FM is still unclear. A recent study has shown that for the pathogenesis of fibromyalgia central pain amplification is the key, FM pathogenesis also known as “central sensitization” is a process that is characterized by increased pain and treatment. sensory in the spinal cord and brain.

The Skin Silence Period (CSP), a spinal reflex interceded by A-delta skin afferents that are used to assess pain management in the central and peripheral nervous systems, between patients with FM and normal healthy controls have been compared by researchers. The number of people analyzed were 24 patients with fibromyalgia (diagnosed according to the classification system of the American College of Rheumatology of 1990) and 24 healthy controls of the same age and sex. CSP was checked from the abductor pollicis brevis muscle which is present in the hand between the wrist and the base of the thumb using standard electro-diagnostic equipment, as well as patient parameters in which statistical information, number sensitive points,

These results suggest that in the central nervous system, fibromyalgia is linked to a dysfunction of the mechanisms of pain modulation. In addition, according to the researchers’ study, there was no correlation between PSC and clinical parameters such as VAS score, K-FIQ score, age and height, which raise questions about the whether or not PSC is used to investigate disease severity. In fact, the researchers point out that further examinations are needed to further assess the relationship between PSC parameters and clinical information.

The authors write in their report: “In conclusion, dysfunction of supraspinal control may be responsible for pain in FM, providing further evidence that central sensitization is the basis of disease pathogenesis.”


Leave a Reply

Your email address will not be published. Required fields are marked *